Denervation of the paraspinal muscles in patients with scoliosis secondary to Chiari malformation and syringomyelia: does it improve following posterior fossa decompression?

Results The initial age and primary curve magnitude averaged 16.0 ± 3.3 years and 63.8° ± 18.3°, respectively. At 7.6 ± 2.6 months post-PFD, significant decreases in mean net gray value, positive area and positive ratio were noted for the 20kd bax protein (P=0.021, 0.013 and <0.001, respectively). The bcl-2 protein, in contrast, appeared to be enriched over the same period in protein lysates. Specifically, the positive area increased from 10.6 ± 6.1 (10) to 21.3 ± 9.2 (10) (P=0.001), while the positive ratio increased from 0.40 ± 0.17 to 0.85 ± 0.19 (P<0.001). Regarding the net gray value, a similar upward trend was observed though not reaching statistical significance (84.4 ± 35.8 versus 101.6 ± 33.3, P =0.197).